Deacetyltanghinin

SKU: orb3179856

Description

Deacetyltanghinin is a selective inhibitor of Na+/K+ATPase, functioning through non-covalent binding, but it exhibits significant cardiotoxicity. Its mechanism involves inhibiting Na+/K+ATPase activity, inducing caspase-mediated apoptosis in cancer cells, and affecting the TXA2-PGI2 balance in rabbit hearts. This compound demonstrates notable anticancer activity, primarily used in targeted research on malignancies such as breast and lung cancer, with attention to its cardiotoxicity regulation.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 4589-95-1
• MW: 548.67
• Formula: C₃₀H₄₄O₉
• SMILES: O[C@@]12[C@@]34[C@@](O3)(C[C@]5([C@@](C)([C@]4(CC[C@]1(C)[C@H](CC2)C=6COC(=O)C6)[H])CC[C@H](O[C@H]7[C@@H](O)[C@H](OC)[C@@H](O)[C@H](C)O7)C5)[H])[H]
• Target: Apoptosis,Prostaglandin Receptor,ATPase,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,Prostaglandin Receptor,ATPase,Caspase