DDR1-IN-1 HCl

SKU: orb1739278

Description

DDR1-IN-1 dihydrochloride is a potent and selective inhibitor of the discoidin domain receptor 1 (DDR1) tyrosine kinase (IC50 = 105 nM), showing 4-fold selectivity over DDR2. This tool compound is useful for investigating DDR1's role in fibrosis and cancer progression in both cellular and animal models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1780303-76-5
• MW: 625.51
• Formula: C₃₀H₃₃Cl₂F₃N₄O₃
• SMILES: Cl.Cl.O=C(NC1=CC=C(C(OC2=CC=C3NC(=O)CC3=C2)=C1)C)C4=CC=C(C(=C4)C(F)(F)F)CN5CCN(CC)CC5
• Target: Others,Discoidin Domain Receptor (DDR)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90489006