DDO-8958

SKU: orb2944494

Description

DDO-8958 is a potent, orally bioavailable, and selective BET BD1 inhibitor with a 5.6 nM KD for BRD4 BD1. It exhibits robust anti-cancer activity in vitro by inhibiting proliferation and migration, inducing apoptosis and cell cycle arrest, and has demonstrated antitumor efficacy in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin, Metabolism Research

Key Properties

• CAS Number: 3017180-18-3
• MW: 407.441
• Formula: C₂₂H₂₂FN₅O₂
• SMILES: FC=1C(=CC(OCC2COC2)=CC1C=3C(=NN(C3C)C)C)C4=CC=NC=5N=CNC54
• Target: Apoptosis,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170556416