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DDO-02267

SKU: orb2945123

Description

DDO-02267 is a potent, selective covalent inhibitor of the RNA demethylase ALKBH5 (IC50 = 0.49 µM). It elevates m6A levels and disrupts the ALKBH5-AXL signaling axis, serving as a valuable chemical probe for studying m6A biology in both cellular and in vivo research contexts.

Research Area

Cardiovascular Research, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2919768-58-2
MW400.362
FormulaC18H12N2O7S
SMILESO=CC=1C=C(C=2C=CC=CC2C1O)S(=O)(=O)NC(=O)C3=NC=CC(=C3)C(=O)O
TargetALK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information