DCLX069

SKU: orb1305127

Description

DCLX069 is a selective PRMT1 inhibitor (IC50 = 17.9 µM) that functions by occupying the S-adenosylmethionine (SAM) binding site. It has demonstrated efficacy in suppressing proliferation in various cancer cell lines, including breast cancer, liver cancer, and acute myeloid leukemia, making it a useful tool for epigenetic and oncology research.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 792946-69-1
• MW: 339.43
• Purity: 98.06% (May vary between batches)
• Formula: C₂₀H₂₅N₃O₂
• SMILES: CCOC(=O)C1=CC(N)=C(C=C1)N1CCN(CC2=CC=CC=C2)CC1
• Target: Histone Methyltransferase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.89 mM);DMSO:60 mg/mL (176.77 mM)

Bioactivity

• Target IC50:
  PRMT1:17.9 μM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anticancer, inhibit, Inhibitor, Histone Methyltransferase, HistoneMethyltransferase, DCLX 069, DCLX069, DCLX-069, PRMT1

Compound Identifiers

PubChem CID

2997002