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dCK1α-2

SKU: orb2802113

Description

dCK1α-2 is an orally bioavailable molecular glue degrader targeting CK1α, which functions to stabilize p53 and upregulate its downstream genes. This compound has demonstrated in vivo antitumor activity in mouse models, supporting its use in p53 pathway and oncology research.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

MW481.93
FormulaC24H24ClN5O4
SMILESO=C1N([C@@H]2C(NC(CC2)=O)=O)CC3=CC(C4=NC5=C(Cl)C(CN6CCOCC6)=N[H]5C=C4)=CC=C31
TargetTLR,Molecular Glues,Casein Kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information