DCAF1 ligand 1

SKU: orb2665020

Description

DCAF1 Ligand 1 (I-653) is the target-binding ligand for the PROTAC CBRD4-DCAF1 degrader-1, demonstrating potent degradation activity with a DC50 in the 10-100 nM range. This compound is a valuable chemical tool for targeted protein degradation research in both cellular and in vivo models to study BRD4 biology and related pathways.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3036941-01-9
• MW: 521.94
• Formula: C₂₈H₂₂ClF₂N₃O₃
• SMILES: C(=O)(C1=C(C(C(N[C@@H](CC(N)=O)C2=CC(Cl)=CC=C2)=O)=CN1)C3=C(C)C(F)=CC=C3F)C4=CC=CC=C4
• Target: Ligands for Target Protein for PROTAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652597