DC-U4106

SKU: orb1686353

Description

DC-U4106 is a small molecule inhibitor targeting USP8 (Kd: 4.7 μM) that induces the degradation of estrogen receptor alpha (ERα) via the ubiquitin-proteasome pathway. It demonstrates potent anti-proliferative activity in breast cancer cell models with low cytotoxicity, supporting its use for in vitro and in vivo research into ER-positive cancers.

Research Area

Cell Biology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2410534-62-0
• MW: 525.56
• Formula: C₂₉H₂₇N₅O₅
• SMILES: Cc1n[nH]c(C)c1Oc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCN(CC1)c1ccccn1
• Target: Apoptosis,Others,DUB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155301443