DC-TEADin02

SKU: orb1685704

Description

DC-TEADin02 is a potent small molecule inhibitor of TEAD auto-palmitoylation with an IC50 of 197 nM. It serves as a valuable research tool for investigating the Hippo signaling pathway in contexts such as cancer research, tissue regeneration, and developmental biology studies, both in vitro and in vivo.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2380228-45-3
• MW: 323.41
• Purity: 99.83% (May vary between batches)
• Formula: C₁₉H₁₇NO₂S
• SMILES: C=CS(=O)(=O)Nc1ccc(Cc2ccc3ccccc3c2)cc1
• Target: YAP
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (10.2 mM);DMSO:90 mg/mL (278.28 mM)

Bioactivity

• In Vitro:
  DC-TEADin02 (0-25 μM) inhibits TEADs transcription activity and downregulates the gene expression of YAP-related downstream.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

YAP–TEAD, DC-TEADin02, DCTEADin02

Compound Identifiers

PubChem CID

155527561