DBCO-(PEG2-VC-PAB-MMAE)2

SKU: orb1988489

Description

This research compound features the cytotoxic payload MMAE, a potent tubulin inhibitor, conjugated via a cleavable DBCO-(PEG2-VC-PAB)2 linker. It is a key component for constructing antibody-drug conjugates (ADCs) and is utilized in both in vitro and in vivo studies for targeted cancer therapy research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2259318-55-1
• MW: 2835.5
• Formula: C₁₄₉H₂₂₄N₂₂O₃₂
• SMILES: C(CCC(N(CCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N2[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C3=CC=CC=C3)C)=O)C)OC)(CCC2)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCOCCOCCC(N[C@H](C(N[C@H](C(NC4=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N5[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C6=CC=CC=C6)C)=O)C)OC)(CCC5)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)C=C4)=O)CCCNC(N)=O)=O)C(C)C)=O)=O)(=O)N7C=8C(C#CC=9C(C7)=CC=CC9)=CC=CC8
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145712369