DBCO-PEG2-Val-Cit-PAB-MMAE

SKU: orb3022071

Description

DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB moiety, and an MMAE payload. The DBCO group serves as a click chemistry handle that can react with azide groups, while the Val-Cit dipeptide is protease-cleavable, enabling the release of the MMAE payload into cells through an elimination mechanism.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2845934-59-8
• MW: 1569.92
• Formula: C₈₄H₁₂₀N₁₂O₁₇
• SMILES: C(CCC(NCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N2[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C3=CC=CC=C3)C)=O)C)OC)(CCC2)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)C=C1)=O)CCCNC(N)=O)=O)[C@H](C)C)=O)=O)(=O)N4C=5C(C#CC=6C(C4)=CC=CC6)=CC=CC5
• Target: ADC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ADC Linker