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DBCO-NHCO-PEG4-amine TFA

SKU: orb3175480

Description

DBCO-NHCO-PEG4-amine TFA is a PROTAC linker (PROTACLinker) belonging to the PEG class. It is a cleavable ADC linker used for conjugating MMAE and antibodies, such as in DBCO-VCpAB MMAE and DBCO-TRX MMAE, with EC50 values of 280 nM and 22 nM against SKBR3 cells, respectively.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetADC Linker,PROTAC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information