DB07268

SKU: orb1304432

Description

DB07268 is a highly selective small molecule inhibitor targeting JNK1. It is utilized in research to investigate JNK1's role in cellular stress responses, apoptosis, and inflammatory pathways, with applications in both in vitro biochemical assays and in vivo disease model studies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 929007-72-7
• MW: 321.33
• Purity: 98.91% (May vary between batches)
• Formula: C₁₇H₁₅N₅O₂
• SMILES: NC(=O)c1ccccc1Nc1ccnc(Nc2cccc(O)c2)n1
• Target: JNK
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.22 mM);DMSO:50 mg/mL (155.6 mM)

Bioactivity

• Target IC50:
  AKT1:15 μM|JNK1:9 nM.|PAK4:5.5 μM|Chk1:0.82 μM|ERK2:25 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DB07268, DB-07268, DB 07268, Inhibitor, JNK1, JNK, inhibit

Compound Identifiers

PubChem CID

16058637