DB07107

SKU: orb1707397

Description

DB07107 is a potent small molecule inhibitor targeting both the drug-resistant Bcr-Abl T315I mutant and Akt1 (IC50: 360 nM). It is a valuable research tool for studying chronic myeloid leukemia (CML) resistance mechanisms and PI3K/Akt signaling pathways in cellular and biochemical assays.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 552332-71-5
• MW: 370.45
• Formula: C₂₃H₂₂N₄O
• SMILES: C([C@H](COC=1C=C(/C=C/C=2C=CN=CC2)C=NC1)N)C=3C=4C(NC3)=CC=CC4
• Target: Bcr-Abl,Akt

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10150362