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DB07006

SKU: orb3174782

Description

DB07006 (compound 18) is a potent ATP-competitive dual inhibitor that targets Wee1 (IC50 = 0.030 μM) and Chk1 checkpoint kinase (IC50 = 0.018 μM). In cellular models, DB07006 effectively blocks the G2/M checkpoint when used in combination with DNA-damaging agents. It holds potential applications in cancer research.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number622855-60-1
MW416.43
FormulaC24H20N2O5
SMILESO=C1NC(=O)C=2C1=C(C=C3C2C=4C=C(O)C=CC4N3CCCO)C=5C=CC=CC5OC
TargetWee1,Chk

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information