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dASK1-VHL

SKU: orb3135364

Description

dASK1-VHL is an orally active PROTAC degrader targeting ASK1. It effectively binds to VHL, promoting the selective degradation of ASK1. By reducing ASK1 protein levels, dASK1-VHL inhibits the activation of p38 MAPK and decreases liver lipid content, offering new insights for MASH research.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

TargetPROTACs,ASK,p38 MAPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information