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Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Catalog Number: orb1302841

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$ 130.00
Catalog Numberorb1302841
CategorySmall Molecules
DescriptionDapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS Number[960404-48-2]
Purity99.88%
MW502.98
SMILESO.O[C@H]1[C@H](O)[C@@H](O)[C@@H](O[C@@H]1CO)c3ccc(Cl)c(Cc2ccc(OCC)cc2)c3.C[C@H](O)CO
FormulaC24H35ClO9
Biological ActivityDapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.