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Catalog Number | orb1302841 |
---|---|
Category | Small Molecules |
Description | Dapagliflozin ((2S)-1,2-propanediol, hydrate) |
CAS Number | [960404-48-2] |
Purity | 99.88% |
MW | 502.98 |
SMILES | O.O[C@H]1[C@H](O)[C@@H](O)[C@@H](O[C@@H]1CO)c3ccc(Cl)c(Cc2ccc(OCC)cc2)c3.C[C@H](O)CO |
Formula | C24H35ClO9 |
Biological Activity | Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |