Dantrolene Na

SKU: orb1310963

Description

Dantrolene sodium is a direct-acting skeletal muscle relaxant that inhibits calcium release from the sarcoplasmic reticulum, uncoupling excitation-contraction. It is widely used in research models of spasticity, malignant hyperthermia, and other neuromuscular disorders, facilitating both in vitro mechanistic studies and in vivo pharmacological investigations.

Research Area

Neuroscience

Key Properties

• CAS Number: 14663-23-1
• MW: 336.23
• Purity: >98%
• Formula: C₁₄H₉N₄O₅ Na
• SMILES: O.[Na+].[O-]C1=NC(=O)CN1\N=C\c1ccc(o1)-c1ccc(cc1)[N+]([O-])=O
• Target: Apoptosis,Calcium Channel,ROS
• Solubility: Soluble in DMSO (up to 3 mg/ml) or in a 1:1 mixture of DMF and Ethanol (up to 20 mg/ml)

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

F440, F-440, F 440, Dantrolene sodium salt, Dantrolene, Dantrolene sodium, CalciumChannel, Calcium Channel, Ryanodine receptor 1

Compound Identifiers

PubChem CID

66553223