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Catalog Number | orb1303229 |
---|---|
Category | Small Molecules |
Description | Dantrolene sodium hemiheptahydrate |
CAS Number | 24868-20-0 |
Purity | 99.72% |
MW | 399.29 |
SMILES | O.O.O.O.O.O.O.[NaH].[NaH].[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)NC2=O)o1.[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)NC2=O)o1 |
Formula | C28H32N8Na2O17 |
Biological Activity | Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction. Dantrolene sodium hemiheptahydrate (Sodium dantrolene) is the sodium salt form of dantrolene, a hydantoin derivative, and direct-acting skeletal muscle relaxant. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥98% | |
24868-20-0 | |
399.29 | |
C14H9N4NaO5 31/2 H2O |