Dalmelitinib

SKU: orb1687131

Description

Dalmelitinib is a potent and selective oral c-Met kinase inhibitor (IC50: 2.9 nM) that targets the ATP-binding site. It inhibits downstream AKT and ERK signaling, suppressing the proliferation of c-Met-driven cancer cells. This compound is a valuable research tool for studying cancers like non-small cell lung cancer in both in vitro and in vivo models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1637658-98-0
• MW: 461.47
• Formula: C₂₂H₁₆FN₇O₂S
• SMILES: S(C1=CC2=C3C(=CN=C2C=C1)N(C)C(=O)CO3)C=4N5C(=NN4)C(F)=CC(=C5)C6=CN(C)N=C6
• Target: Others,c-Met/HGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

86302574