Dacomitinib metabolite M2

SKU: orb1987184

Description

Dacomitinib metabolite M2, also identified as the dacomitinib cysteine conjugate, is a potent inhibitor of both wild-type EGFR and the T790M mutant. This small molecule is used in biochemical and cellular research to study EGFR-driven signaling pathways and resistance mechanisms in vitro.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1262034-38-7
• MW: 591.1
• Formula: C₂₇H₃₂ClFN₆O₄S
• SMILES: N(C=1C2=C(C=C(OC)C(NC(CC(CN3CCCCC3)SC[C@@H](C(O)=O)N)=O)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4
• Target: Others,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

119058027