Dacomitinib Intermediate 2

SKU: orb1962262

Description

Dacomitinib Intermediate 2 is a synthetic precursor of the EGFR inhibitor dacomitinib. This compound, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine, is used in cancer research, particularly for studying non-small cell lung cancer mechanisms in biochemical and cellular assays.

Key Properties

• CAS Number: 179552-74-0
• MW: 348.72
• Purity: 99.27% (May vary between batches)
• Formula: C₁₅H₁₀ClFN₄O₃
• SMILES: COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1[N+]([O-])=O
• Target: Others
• Solubility: DMSO:16.67 mg/mL (47.8 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine

Compound Identifiers

PubChem CID

21847811