[D-Trp7,9,10]-Substance P

SKU: orb1679418

Description

This selective Substance P analog acts as an M1 muscarinic receptor antagonist by specifically blocking Gq/11 protein activation, while sparing M2 receptor-mediated Gi/o signaling. It is a valuable research tool for studying cholinergic pathways and receptor-specific G-protein coupling in both cellular and tissue-based experimental models.

Research Area

Neuroscience

Key Properties

• Target: AChR
• CAS Number: 89430-38-6
• MW: 1588.89
• Formula: C₇₉H₁₀₅N₂₁O₁₃S
• SMILES: C([C@H](C(N[C@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CCSC)C(N)=O)=O)=O)NC([C@@H](NC([C@@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC(=O)[C@H]6N(C([C@H](CCCNC(=N)N)N)=O)CCC6)CCCCN)=O)CCC5)CCC(N)=O)=O)CCC(N)=O)=O)=O)CC7=CC=CC=C7)=O)C=8C=9C(NC8)=CC=CC9

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

16143852