D-tetrahydropalmatine

SKU: orb1302346

Description

D-Tetrahydropalmatine is a selective inhibitor of the organic cation transporter 1 (OCT1). It effectively blocks monocrotaline (MCT) uptake in vitro, as demonstrated in MDCK-hOCT1 cells and primary rat hepatocytes, thereby reducing MCT-induced cytotoxicity. This makes it a valuable pharmacological tool for studying hepatic drug transport and toxin metabolism in experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3520-14-7
• MW: 355.43
• Purity: 99.89% (May vary between batches)
• Formula: C₂₁H₂₅NO₄
• SMILES: [H][C@@]12Cc3ccc(OC)c(OC)c3CN1CCc1cc(OC)c(OC)cc21
• Target: Dopamine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.63 mM);DMSO:25 mg/mL (70.34 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dopamine Receptor, Dopamine, DopamineReceptor, Dtetrahydropalmatine, D-tetrahydropalmatine, D-Tetrahydropalmatine, D tetrahydropalmatine, inhibit, Inhibitor

Compound Identifiers

PubChem CID

72301