D-Pantothenic acid

SKU: orb1223981

Description

D-Pantothenic acid, also called vitamin B5, is a water-soluble vitamin and an essential nutrient for many animals.

Key Properties

• CAS Number: 79-83-4
• MW: 219.24
• Purity: >98% (HPLC)
• Formula: C₉H₁₇NO₅
• SMILES: CC(C)(CO)[C@H](C(=O)NCCC(=O)O)O
• Target: Others
• Solubility: DMSO:44 mg/mL (200.69 mM); Ethanol:<1 mg/mL (<1 mM); Water:44 mg/mL (200.69 mM)

Bioactivity

• In Vivo:
  Pantothenic acid (PTA; 3x10, 3x100, and 3x300 mg/kg) decreases Valproic acid (VPA; 300, 400, and 500 mg/kg, s. c.)-induced neural tube defects in mice. Animal model: Female ICR mice weighing 29-35 g. Dosage: 3x10, 3x100, and 3x300 mg/kg (10 mL/kg, volume administered). Administration: Injected intraperitoneally (i.p.) on day 8.5 of gestation. Result: Significantly reduced VPA (300, 400, and 500 mg/kg, s. c.)-induced exencephaly, while none of the other external malformations such as open eyelid or skeletal malformations such as fused, absent, or bifurcated ribs and fused thoracic vertebrae and fused sternebrae were reduced.
• In Vitro:
  D-Pantothenic acid sodium is a precursor to coenzyme A and is primarily involved in energy production and lipid metabolism through the TCA cycle and the β-oxidation pathway, respectively.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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