D-α-Methyl DOPA

SKU: orb3173960

Description

D-α-Methyl DOPA is an inhibitor of DQ8 peptide binding to MHC class II molecules. By occupying a binding site in the DQ8 peptide groove, D-α-Methyl DOPA prevents the DQ8 peptide from associating with MHCII molecules. This action blocks presentation to CD4+ T cells, thereby slowing or hindering the onset or progression of type 1 diabetes or celiac disease.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2799-15-7
• MW: 211.22
• Formula: C₁₀H₁₃NO₄
• SMILES: C([C@@](C(O)=O)(C)N)C1=CC(O)=C(O)C=C1
• Target: MHC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

MHC