Dihydrosphingosine

SKU: orb1710787

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Description

This small molecule inhibitor selectively targets cytosolic phospholipase A2 alpha (cPLA2α), blocking its activity and the subsequent release of arachidonic acid. It is a valuable research tool for studying lipid signaling pathways in inflammation and apoptosis, applicable in both cellular and biochemical assay systems.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	764-22-7
MW	301.5
Purity	>98%
Formula	C₁₈H₃₉NO₂
SMILES	CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO
Target	Kinase
Solubility	Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Bioactivity

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In Vitro	In PC12 cells, D-Erythro-dihydrosphingosine inhibits mastoparan-stimulated arachidonic acid release. D-Erythro-dihydrosphingosine (100 μM) slightly inhibits [3H]Arachidonic acid release.

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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D-erythro-sphinganine

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Compound Identifiers

PubChem CID

91486 ↗

Key Properties

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No computed properties available.

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