Dihydrosphingosine

SKU: orb1710787

Description

This small molecule inhibitor selectively targets cytosolic phospholipase A2 alpha (cPLA2α), blocking its activity and the subsequent release of arachidonic acid. It is a valuable research tool for studying lipid signaling pathways in inflammation and apoptosis, applicable in both cellular and biochemical assay systems.

Research Area

Metabolism Research

Key Properties

• CAS Number: 764-22-7
• MW: 301.5
• Purity: >98%
• Formula: C₁₈H₃₉NO₂
• SMILES: CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO
• Target: Kinase
• Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Bioactivity

• In Vitro:
  In PC12 cells, D-Erythro-dihydrosphingosine inhibits mastoparan-stimulated arachidonic acid release. D-Erythro-dihydrosphingosine (100 μM) slightly inhibits [3H]Arachidonic acid release.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

D-erythro-sphinganine

Compound Identifiers

PubChem CID

91486