CZY43

SKU: orb2945164

Description

CZY43 is an HER3 degrader that effectively induces degradation of HER3 in breast cancer SKBR3 cells in a dose- and time-dependent manner. It efficiently inhibits HER3-dependent signaling and cancer cell growth, outperforming Bosutinib.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• MW: 746.808
• Formula: C₄₂H₅₃Cl₂N₅O₃
• SMILES: COC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=C(C=C3Cl)Cl)OC)OCCCN4CCC5(CC4)CCN(CC5)CCC67CC8CC(C6)CC(C8)C7
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR