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CZY43

CZY43

Catalog Number: orb2945164

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Product Properties
Catalog Numberorb2945164
CategorySmall Molecules
DescriptionCZY43 is an HER3 degrader that effectively induces degradation of HER3 in breast cancer SKBR3 cells in a dose- and time-dependent manner. It efficiently inhibits HER3-dependent signaling and cancer cell growth, outperforming Bosutinib.
TargetEGFR
MW746.808
FormulaC42H53Cl2N5O3
SMILESCOC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=C(C=C3Cl)Cl)OC)OCCCN4CCC5(CC4)CCN(CC5)CCC67CC8CC(C6)CC(C8)C7
Storage-20°C
Research AreaCardiovascular Research, Signal Transduction
NoteFor research use only
Expiration Date12 months from date of receipt.
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