CZL55

SKU: orb1744071

Description

CZL55 is a potent and low-cytotoxicity caspase-1 inhibitor (IC50 = 0.024 µM). It is a valuable research tool for studying the role of caspase-1 and inflammasome signaling in models of febrile seizures, both in vitro and in vivo.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 667408-87-9
• MW: 386.4
• Purity: 98.19%
• Formula: C₂₀H₂₂N₂O₆
• SMILES: N(C(=O)C1=CC(NC(CCCC(O)=O)=O)=CC=C1)C2=C(OC)C=C(OC)C=C2
• Target: Caspase
• Solubility: DMSO:100 mg/mL (258.8 mM)

Bioactivity

• Target IC50:
  Caspase-1:24 nM

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Caspase-1

Compound Identifiers

PubChem CID

1217703