CZC-8004

SKU: orb1299999

Description

CZC-8004 is a multi-targeted tyrosine kinase inhibitor with potent activity against ABL kinase. It is utilized in biochemical and cellular assays to study kinase signaling pathways and has been employed in preclinical research for investigating oncogenic mechanisms in relevant in vitro models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 916603-07-1
• MW: 309.34
• Purity: 99.29% (May vary between batches)
• Formula: C₁₇H₁₆FN₅
• SMILES: NCc1ccc(Nc2ncc(F)c(Nc3ccccc3)n2)cc1
• Target: Bcr-Abl,EGFR,VEGFR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.47 mM);DMSO:77.5 mg/mL (250.53 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Epidermal growth factor receptor, EGFR, ErbB-1, Inhibitor, HER1, inhibit, CZC 00008004, CZC 8004, CZC00008004, CZC-00008004, CZC8004, CZC-8004, aminopyrimidine, BcrAbl, Bcr-Abl, Abl, tyrosine kinases, VEGFR, Vascular endothelial growth factor receptor

Compound Identifiers

PubChem CID

15980598