Cytochalasin D

SKU: orb1696852

Description

Cytochalasin D is a cell-permeable actin polymerization inhibitor used in research to study cytoskeletal dynamics. It has been applied in vitro to investigate chondrogenesis, phagocytosis, and smooth muscle contraction, and in vivo to study tumor growth and metastasis in mouse models.

Research Area

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 22144-77-0
• MW: 507.62
• Purity: 99.58% (May vary between batches)
• Formula: C₃₀H₃₇NO₆
• SMILES: [H][C@]12[C@H](Cc3ccccc3)NC(=O)[C@@]11[C@H](OC(C)=O)\C=C\[C@@](C)(O)C(=O)[C@@H](C)C\C=C\[C@@]1([H])[C@H](O)C(=C)[C@H]2C
• Target: YAP,Akt,Arp2/3 Complex,ATPase,p38 MAPK,Calcium Channel,PI3K,Factor VIIa,Antibiotic

Storage & Handling

• Storage: store at low temperature,keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Akt, ATPase, CalciumChannel, Calcium Channel, Cytochalasin D, PI3K, p38MAPK, p38 MAPK

Compound Identifiers

PubChem CID

124523547