Cys-GE11

SKU: orb3180365

Description

Cys-GE11 is a cysteine-modified short peptide. It can link with PEG-P(TMC-DTC) through the N-terminus of cysteine to form a targeting polymer. Cys-GE11 targets cells with high EGFR expression, such as SMMC-7721 cells. This compound significantly enhances drug accumulation at tumor sites and exhibits low toxicity.

Key Properties

• Target: EGFR
• CAS Number: 1421680-54-7
• MW: 1643.84
• Formula: C₇₈H₁₀₂N₁₈O₂₀S
• SMILES: C([C@H](NC([C@H](CC1=CN=CN1)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CS)N)=O)=O)=O)C(N[C@@H](CC3=CC=C(O)C=C3)C(NCC(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@H](C(=O)N5[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)[C@@H](C)C)=O)CC(N)=O)=O)CCC(N)=O)=O)CCC5)[C@@H](C)O)=O)=O)=O)=O)C=6C=7C(NC6)=CC=CC7

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR