Cyromazine

SKU: orb1310241

Description

Cyromazine (CGA-72662) is an FDA-approved insect growth regulator and ectoparasiticide with specific activity against dipterous larvae. It is used in livestock and researched in entomology for in vivo and in vitro studies on insect development and control.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 66215-27-8
• MW: 166.18
• Purity: 99.18% (May vary between batches)
• Formula: C₆H₁₀N₆
• SMILES: N(C=1N=C(N)N=C(N)N1)C2CC2
• Target: Endogenous Metabolite
• Solubility: Ethanol:2 mg/mL (12.04 mM);H2O:1 mg/mL (6.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (30.09 mM);DMSO:60 mg/mL (361.05 mM)

Bioactivity

• In Vivo:
  Cyromazine may act at certain stages of cuticle sclerotization, with little to no effect on dihydrofolate reductase and the activity of aminomethylphosphonic acid. It alters the percentage or total content of phenylalanine and tyrosine amino acids in the pupal exoskeleton cuticle, resulting in larvae exhibiting typical signs of Cyromazine intoxication. The mechanism of action likely involves inhibiting the synthesis of chitin and scleroprotein.
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• In Vitro:
  In both plants and animals, Cyromazine undergoes dealkylation metabolism and, through environmental degradation, forms melamine.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyromazin, Cyromazine, CGA72662, CGA-72662, CGA 72662, inhibit, EndogenousMetabolite, Endogenous Metabolite, Inhibitor

Compound Identifiers

PubChem CID

47866