CYP51/PD-L1-IN-3

SKU: orb2277720

Description

CYP51/PD-L1-IN-3 (L21) is a dual-target quinazoline inhibitor of fungal CYP51 and PD-L1, demonstrating potent in vitro antifungal activity. Its mechanism involves inducing mitochondrial dysfunction, ROS accumulation, and suppression of key inflammatory proteins like NLRP3, leading to fungal apoptosis and cell death. This profile supports its research application in studying fungal pathogenesis and immunomodulation.

Research Area

Cell Biology, Immunology & Inflammation, Immunology & Inflammation; Metabolism Research, Infectious Disease & Virology, Metabolism Research

Key Properties

• MW: 468.55
• Formula: C₂₇H₂₈N₆O₂
• Target: Cytochromes P450,Others,PD-1/PD-L1,Antifungal

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Cytochromes P450,Others,PD-1/PD-L1,Antifungal