Cynomolgus Latent TGF-beta 1 Protein, His Tag

• Catalog Number: orb668909
• Category: Proteins
• Description: Cynomolgus Latent TGF-Beta 1 (C33S), His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 30 - Ser 390 (C33S) (Accession # XP_005589396.1).
• Target: Latent TGF-beta 1
• Conjugation: Unconjugated
• Tag: N-10×His
• Reactivity: Monkey
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, pH 7.4
• Purity: 90%
• Protein Sequence: Leu 30 - Ser 390 (C33S)
• UniProt ID: A0A2K5TJB2
• MW: 43.1 kDa
• Application notes: This protein carries a polyhistidine tag at the N-terminus. The precursor proprotein is partially cleaved by FURIN to form mature Transforming growth factor beta-1 (TGF-beta-1) and Latency-associated peptide (LAP) chains with calculated MW of 12.7 kDa and 30.4 kDa respectively. The protein migrates as 50-60 kDa (precursor proprotein), 38-45 kDa (LAP) and 13 kDa (TGFB1) under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression System: HEK293
• Endotoxins: 1.0 EU per μg
• Biological Origin: Cynomolgus
• Expression Region: Leu 30 - Ser 390 (C33S)
• Storage: -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
• Note: For research use only