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| Catalog Number | orb1786194 |
|---|---|
| Category | Proteins |
| Description | Cynomolgus Integrin alpha V beta 3 Heterodimer Protein, His Tag |
| Target | Integrin alpha V beta 3 |
| Conjugation | Unconjugated |
| Tag | C-10×His | Native |
| Reactivity | Monkey |
| Form/Appearance | Powder |
| Buffer/Preservatives | 50 mM Tris, 150 mM NaCl, pH 8.0 |
| Purity | 90% |
| UniProt ID | A0A2K5WYN9, A0A2K5WCD3 |
| MW | 113 kDa & 81.7kDa |
| Application notes | Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAV and ITGB3, has a calculated MW of 113 kDa (ITGAV) and 81.7 kDa (ITGB3). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB3 contains no tag but a basic tail at the C-terminus. The protein migrates as 150 kDa (ITGAV) and 90 kDa (ITGB3) when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation. |
| Expression System | HEK293 |
| Endotoxins | 1.0 EU per μg |
| Expression Region | Phe 31 - Pro 993 & Gly 27 - Asp 718 |
| Storage | -20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower |
| Research Area | Disease Biomarkers |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
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