Cyclosporin H

SKU: orb1306329

Description

Cyclosporin H is a specific FPR1 inhibitor that attenuates inflammatory lung injury in ALI models by suppressing MAPK and AKT pathways. It also serves as a potent lentiviral transduction enhancer in hematopoietic stem cells and exhibits additive effects when combined with Rapamycin or PGE2, all without the immunosuppressive activity of Cyclosporin A.

Key Properties

• Target: Others
• CAS Number: 83602-39-5
• MW: 1202.61
• Purity: 97.68% (May vary between batches)
• Formula: C₆₂H₁₁₁N₁₁O₁₂
• SMILES: [C@H]([C@@H](C/C=C/C)C)(O)[C@@]1(N(C)C(=O)[C@@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclosporin H, inhibit, FPR1, lentiviral, Inhibitor, transduction, viral

Compound Identifiers

PubChem CID

51340731