Cyclosporin D

SKU: orb1983873

Description

Cyclosporin D is a metabolite of the immunosuppressant Cyclosporin A. It functions by binding cyclophilin D and inhibiting calcineurin phosphatase activity, thereby modulating T-cell activation. This mechanism supports its use in research applications involving immunology, transplantation, and T-cell signaling pathways in both in vitro and in vivo models.

Key Properties

• Target: Others
• CAS Number: 63775-96-2
• MW: 1216.662
• Formula: C₆₃H₁₁₃N₁₁O₁₂
• SMILES: C\C=C\C[C@@H](C)[C@@H](O)[C@@H]1N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@@H](NC1=O)C(C)C)C(C)C

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5287819