Cyclorasin 9A5 TFA

SKU: orb2802041

Description

Cyclorasin 9A5 TFA is a cell-permeable cyclic peptide inhibitor of the Ras-Raf protein-protein interaction, exhibiting an IC50 of 120 nM. This tool compound is used in vitro to study oncogenic MAPK/ERK pathway signaling and has been applied in cellular models of Ras-driven cancers.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• Target: Raf,Ras
• MW: 1586.82 (free base)
• Formula: C₇₅H₁₀₈FN₂₅O₁₃.xC₂HF₃O₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Raf,Ras