Cyclopenta[c][1]benzopyran-8-ol, 1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-, (3aR,4S,9bS)-rel-

SKU: orb1297871

Description

This compound is a selective estrogen receptor beta (ERβ) agonist with the relative stereochemistry (3aR,4S,9bS). It is a research chemical used to study ERβ-specific signaling pathways in both cellular (in vitro) and animal (in vivo) models of neuroprotection, inflammation, and metabolism.

Research Area

Metabolism Research

Key Properties

• CAS Number: 533883-77-1
• MW: 282.33
• Purity: 99.96% (May vary between batches)
• Formula: C₁₈H₁₈O₃
• SMILES: OC=1C=C2[C@@]3([C@]([C@H](OC2=CC1)C4=CC=C(O)C=C4)(CCC3)[H])[H]
• Target: Estrogen/progestogen Receptor,Estrogen Receptor/ERR
• Solubility: DMSO:55 mg/mL (194.81 mM)

Bioactivity

• Target IC50:
  ERβ:3.61 nM (EC50)|ERβ:1.54 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclopenta[c][1]benzopyran 8 ol, 1,2,3,3a,4,9b hexahydro 4 (4 hydroxyphenyl) , (3aR,4S,9bS) rel , Cyclopenta[c][1]benzopyran8ol, 1,2,3,3a,4,9bhexahydro4(4hydroxyphenyl), (3aR,4S,9bS)rel, ERRβ, Estrogen Receptor, EstrogenReceptor, progestogenReceptor, progestogen Receptor

Compound Identifiers

PubChem CID

9925763