Cyclo(his-pro) TFA

SKU: orb3177695

Description

Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to thyrotropin-releasing hormone, demonstrates inhibitory effects on NF-κB nuclear accumulation. Cyclo(his-pro) TFA additionally possesses the capacity to cross the blood-brain barrier and modulate multiple inflammatory and stress-associated responses. Cyclo(his-pro) TFA is therefore applicable to neuroinflammation, neuroendocrine regulation, and central nervous system signaling investigations.

Research Area

Signal Transduction

Key Properties

• CAS Number: 936749-56-3
• MW: 348.28
• Purity: 99.94% (May vary between batches)
• Formula: C₁₃H₁₅F₃N₄O₄
• SMILES: C(C(O)=O)(F)(F)F.O=C1N2[C@](C(=O)N[C@H]1CC3=CN=CN3)(CCC2)[H]
• Target: NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB