Cyclo(-RGDfK)

SKU: orb1300445

Description

Cyclo(-RGDfK) is a highly potent and selective αvβ3 integrin inhibitor (IC50 = 0.94 nM). It is widely used in cancer research to study tumor angiogenesis and metastasis through its targeted binding to αvβ3 on endothelial and cancer cells in both in vitro and in vivo models.

Research Area

Signal Transduction

Key Properties

• Target: Integrin
• CAS Number: 161552-03-0
• MW: 603.67
• Purity: >99.99% (May vary between batches)
• Formula: C₂₇H₄₁N₉O₇
• SMILES: NCCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

-RGDfK, αvβ3 integrin, αVβ3 integrin, tumoral cell, cancer, Cyclo(RGDfK), Cyclo(-RGDfK), Cyclo( RGDfK), Cyclo, Cyclo (-RGDfK), Inhibitor, Integrin, Microvasculature, inhibit, ligand

Compound Identifiers

PubChem CID

10196873