Cyclin A/B RxL-IN-1

SKU: orb3173176

Description

Cyclin A/B RxL-IN-1 is an inhibitor targeting the interaction between Cyclin A/B RxL and the hydrophobic patch (HP). It exhibits an IC50 of 0.12 μM for inhibiting Cyclin A. In xenograft models derived from murine cell lines (CDX), Cyclin A/B RxL-IN-1 demonstrates antitumor efficacy. CDK-IN-19 is applicable for research on E2F-driven cancers, including small cell lung cancer (SCLC).

Research Area

Cell Biology

Key Properties

• CAS Number: 3036231-62-3
• MW: 972.95
• Formula: C₄₆H₆₃Cl₂F₄N₇O₇
• SMILES: C(=O)(C1(C(F)(F)F)CC2(C1)CCC2)N3[C@H](C(N[C@H](C(N(C)[C@@H]4C(=O)N[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC5=C(Cl)C=CC(Cl)=C5)C(=O)NC(C)(C)C(=O)NCCCC4)=O)[C@H]6CC6)=O)C[C@@H](F)C3
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CDK