Cyanidin Chloride

SKU: orb1301720

Description

Cyanidin Chloride, the primary anthocyanin antioxidant in Vitis vinifera, shows research potential for mitigating diabetes mellitus complications, particularly in liposomal delivery systems. In vitro and in vivo studies investigate its role in oxidative stress and metabolic pathways relevant to diabetic pathology.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 528-58-5
• MW: 322.70
• Purity: 99.63% (May vary between batches)
• Formula: C₁₅H₁₁ClO₆
• SMILES: [Cl-].Oc1cc(O)c2cc(O)c([o+]c2c1)-c1ccc(O)c(O)c1
• Target: RANKL/RANK,Antioxidant
• Solubility: DMSO:22.50 mg/mL (69.72 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.00 mg/mL (6.20 mM)

Bioactivity

• In Vitro:
  Cyanidin Chloride inhibits RANKL-induced NF-κB activation, suppresses the degradation of IκB-α and attenuates the phosphorylation of extracellular signal-regulated kinases (ERK). In addition, Cyanidin Chloride abrogated RANKL-induced calcium oscillations, the activation of nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1), and the expression of c-Fos. Further.Cyanidin Chloride protects against ovariectomy-induced bone loss in vivo.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyanidin, Cyanidin Chloride, Antioxidant, IdB 1027, IdB1027, IdB-1027, Inhibitor, inhibit, RANKL/RANK

Compound Identifiers

PubChem CID

68247