CX-5461 dihydrochloride

• Catalog Number: orb1685890
• Category: Small Molecules
• Description: CX-5461 dihydrochloride
• Purity: 98%
• MW: 586.54
• Formula: C₂₇H₂₉Cl₂N₇O₂S
• Biological Activity: CX-5461 dihydrochloride is a potent, orally active inhibitor of Pol I-mediated rRNA synthesis that acts on HCT-116 cells (IC50: 142 nM), A375 cells (IC50: 113 nM) and MIA PaCa-2 cells (IC50: 54 nM), and to a lesser extent on Pol II (IC50 ≥ 25 μM).
• Note: For research use only
• Expiration Date: 12 months from date of receipt.