CX-157

SKU: orb1707416

Description

CX-157 (KP 157) is a selective MAO-A inhibitor used in neuroscience and oncology research. It is applied in studies investigating depression-like behaviors in animal models and has been examined in vitro for its effects on cancer cell lines.

Research Area

Metabolism Research, Neuroscience

Key Properties

• CAS Number: 205187-53-7
• MW: 348.27
• Purity: 99.35% (May vary between batches)
• Formula: C₁₄H₈F₄O₄S
• SMILES: O=S1(=O)C2=CC=C(F)C=C2OC3=CC(OCC(F)(F)F)=CC=C31
• Target: Monoamine Oxidase,MAO

Bioactivity

• Target IC50:
  MAO-A:19.3 ng/ml（EC50）|MAO-A:（EC50）19.3 ng/ml
• In Vivo:
  CX157 (60 and 80 mg) significantly inhibited the binding of [(11)C]clorgyline to brain MAO-A by 47-72% at 2 hours post-administration, with complete recovery of brain MAO-A by 24 hours post-dosing.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CX 157, CX157, CX-157, MAO-A, KP 157

Compound Identifiers

PubChem CID

18687754