CVN14

SKU: orb3210439

Description

CVN14 is an efficient and selective CD38 inhibitor that can penetrate the blood-brain barrier, with an IC50 of 19 nM in humans and 2.4 nM in mice. It binds non-competitively with CD38 and ADPR to form a complex, thereby inhibiting CD38 enzyme activity. CVN14 is applicable for research into neurodegenerative diseases.

Key Properties

• CAS Number: 2925663-26-7
• MW: 382.38
• Formula: C₁₇H₂₁F₃N₆O
• SMILES: C(N[C@@H]1CC[C@@H](NCC(F)(F)F)CC1)(=O)C2=NC(=NC(C)=C2)N3C=CN=C3
• Target: CD38

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CD38