Curdione

SKU: orb1304226

Description

Curdione ((+)-Curdione) is a bioactive small molecule that inhibits CYP3A4 enzyme activity and suppresses prostaglandin E2 production, indicating anti-inflammatory potential. It also induces apoptosis and inhibits proliferation in MCF-7 breast cancer cells in vitro, supporting its investigation as a chemopreventive agent.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 13657-68-6
• MW: 236.35
• Purity: 99.99% (May vary between batches)
• Formula: C₁₅H₂₄O₂
• SMILES: CC(C)[C@@H]1CC(=O)[C@@H](C)CC\C=C(C)\CC1=O
• Target: Nrf2,Indoleamine 2,3-Dioxygenase (IDO),TGF-beta/Smad,ROS,Ferroptosis,Apoptosis,IDO,Cytochromes P450,Autophagy,Glutathione Peroxidase
• Solubility: DMSO:55 mg/mL (232.71 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.46 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Curdione, CYP3A4, (+)-Curdione, Inhibitor, inhibit

Compound Identifiers

PubChem CID

6441391