CU06-1004

• Catalog Number: orb1942107
• Category: Small Molecules
• Description: CU06-1004 (Sac-1004) is an orally active compound that mitigates endothelial dysfunction by inhibiting hyperpermeability and inflammation. It reduces vascular leakage and inflammation in multiple animal models, including diabetic retinopathy, stroke, cancer, and inflammatory bowel disease. CU06-1004 also improves conditions in a CDAA-induced mouse model of NASH and enhances cardiac function [1] [2] [3].
• CAS Number: 1296734-08-1
• Purity: 98.00%
• MW: 626.82
• SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](OC5O[C@H](COC(C)=O)[C@@H](OC(C)=O)C=C5)CC4)(CC1)[H])[H])(CC[C@@H]2\C(=C\CCCC(OC)=O)\C)[H]
• Formula: C₃₇H₅₄O₈
• Biological Activity: CU06-1004 (Sac-1004) is an orally active compound that acts as an endothelial dysfunction blocker. It mitigates endothelial dysfunction by inhibiting hyperpermeability and inflammation. The compound demonstrates efficacy in reducing vascular leakage and inflammation across multiple animal models, including those for diabetic retinopathy, stroke, cancer, and inflammatory bowel disease. Additionally, CU06-1004 improves conditions in a CDAA-induced mouse model of NASH and enhances cardiac function [1] [2] [3].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.