CU-32

SKU: orb1692108

Description

CU-32 is a selective cGAS inhibitor (IC50=0.45 µM) that suppresses DNA-induced IFN-β production in THP-1 cells without affecting RIG-I or TLR pathways. This tool compound is used in vitro to study the cGAS-STING signaling axis in autoimmunity, viral infection, and cancer-related inflammation research.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2400954-16-5
• MW: 371.13
• Formula: C₁₁H₁₀IN₅O₂
• SMILES: N(C=1N=C(C(OC)=O)N=C(N)N1)C2=CC=C(I)C=C2
• Target: cGAS,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146317014